Systematic: How Systems Biology Is Transforming Modern Medicine
Working the systems
In traditional biology, a biologist might study how a single protein works, but systems biology looks at how networks of proteins work together. Systematic introduces us to the field that is revolutionizing both medicine and our understanding of living things.
Breakthroughs became possible only when computer technology enabled researchers to process massive amounts of data to study complete systems. The result has been progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual, insights into how the brain works, and the discovery that microbes that live in the gut may drive malnutrition and obesity.
Systematic is a compellingly readable primer on a field that is changing the very essence of science.
"Enthusiastic and young-he is currently pursuing a doctorate in biology at Harvard-Valcourt delivers an expert overview of a spectacularly burgeoning field where, for example, a team of scientists spent 12 years and $3 billion sequencing the human genome in 2003. By 2016, a single scientist could do the same in a day for roughly $1,000....Mixing interviews, anecdotes, and lucid explanations, the author describes how dividing fertilized cells, at first identical, learn how to become a complete organism. He shares the universal amazement at how organs such as the brain develop seemingly magical (i.e., "emergent") properties absent from their individual components, and he concludes that researchers and their supercomputers will transform lives, cure diseases, design drugs and perhaps living things from scratch, and efficiently correct a defective genome in an adult."-Kirkus Reviews
"Systems biologists seem on the verge of achieving great things, and Valcourt delivers a lucid introduction to this ingenious combination of the hard sciences and advanced technology that adopts a holistic view of natural phenomena."-Publishers Weekly
About the Author
James R. Valcourt is pursuing a Ph.D. in systems biology at Harvard University. As a former researcher at D. E. Shaw Research in New York City, he used supercomputer simulations to study pharmaceutical drugs. He is a recipient of the quarter-million-dollar Hertz Foundation Graduate Fellowship.
Additional Book Details
|Release Date:||February 7, 2017|